Deposition of bolus and continuously inhaled aerosols in rhythmically moving terminal alveoli

Pulmonary Deposition and Retention of Inhaled Aerosols

tendency to pulmonary collapse produced by oxygen breathing and acceleration combined. The second section considers problems of engineering space vehicles and space ecology or providing a satisfactory environment for man. As Konecci puts it, "Man is an essential part of space exploration; in fact, he is the reason for space exploration." Space ecology is really the crux of the whole thing. We c...

Leeward deposition of particles on cylinders from moving aerosols.

Comparative deposition of inhaled aerosols in experimental animals and humans: a review.

The biological effects of inhaled aerosols are often related to their site(s) of deposition within the respiratory tract. However, deposition patterns may differ between humans and those experimental animals commonly used in inhalation toxicology studies, making cross-species risk extrapolations difficult. This paper reviews the factors that control deposition and synthesizes much of the availa...

Lung Deposition Analyses of Inhaled Toxic Aerosols in Conventional and Less Harmful Cigarette Smoke: A Review

Inhaled toxic aerosols of conventional cigarette smoke may impact not only the health of smokers, but also those exposed to second-stream smoke, especially children. Thus, less harmful cigarettes (LHCs), also called potential reduced exposure products (PREPs), or modified risk tobacco products (MRTP) have been designed by tobacco manufacturers to focus on the reduction of the concentration of c...

Gravitational deposition in a rhythmically expanding and contracting alveolus.

In a previous simulation, our laboratory demonstrated that the flow induced by a rhythmically expanding and contracting alveolus is highly complex (Haber S, Butler JP, Brenner H, Emanuel I, and Tsuda A, J Fluid Mech 405: 243-268, 2000). Based on these earlier findings, we hypothesize that the trajectories and deposition of aerosols inside the alveoli differ substantially from those previously p...